Keyjuan Brown Sparks No. 23 Louisville Past No. 16 SMU 41-31 With Career-High 163 Yards
No. 23 Louisville found its biggest plays when it needed them most Saturday, using an explosive rushing attack and three SMU turnovers to defeat the No. 16 Mustangs 41-31 at L&N Stadium.
In a game that featured eight lead changes, Keyjuan Brown delivered the decisive performance. The Louisville running back rushed for a career-high 163 yards and two touchdowns on just 10 carries, including scoring runs of 58 and 53 yards in the second half.
SMU running back Kendrick Raphael answered with a career-best performance of his own, rushing for 197 yards and three touchdowns, but Louisville scored the final 13 points and forced a crucial late turnover near the goal line to secure the victory.
The Cardinals improved to 2-1 overall and 1-0 in the ACC, while SMU fell to 2-1 and 1-1 in conference play.
SMU Takes a Narrow Lead Into Halftime
The first half established the back-and-forth nature of the matchup.
Neither team was able to create lasting separation, with Louisville quarterback Lincoln Kienholz and SMU quarterback Kevin Jennings directing offenses that repeatedly exchanged momentum.
By halftime, the Mustangs had managed to build a 17-14 advantage.
SMU had opportunities to build on that lead, but the Mustangs' inability to protect the football would eventually become one of the defining differences.
Louisville entered the game without committing a turnover through its first two contests and extended that streak against SMU. The Cardinals finished their third consecutive game without giving the ball away.
SMU would not enjoy the same success.
Keyjuan Brown Changes the Game With One Run
Louisville needed less than a minute after halftime to erase SMU's lead.
Keyjuan Brown broke through the Mustangs defense for a 58-yard touchdown, immediately putting Louisville back in front.
The run provided a glimpse of what was coming.
Louisville had lacked the explosive rushing plays that had been a major part of its offense in previous seasons. Against SMU, that element returned.
The Cardinals finished with 265 rushing yards on 37 carries, producing eight runs of at least 12 yards.
Keyjuan Brown was at the center of the turnaround.
His 163 yards came on only 10 carries, giving him an average of more than 16 yards per attempt.
Kendrick Raphael Keeps SMU in Front
Louisville's rushing success did not go unanswered.
Raphael delivered the best rushing performance of his SMU career, repeatedly breaking through the Cardinals defense and keeping the Mustangs in position to win.
He finished with 197 yards and three touchdowns, establishing a new career high in rushing yards while tying his personal best for touchdowns.
His biggest score came in the fourth quarter.
With SMU trailing 28-24, Raphael scored on a 12-yard touchdown run with 11:33 remaining, putting the Mustangs back in front 31-28.
After eight lead changes, SMU had regained control with less than 12 minutes remaining.
It lasted just 91 seconds.
Keyjuan Brown Answers With 53-Yard Touchdown
Louisville responded immediately.
With 10:02 remaining, Keyjuan Brown broke free again, this time racing 53 yards for his second touchdown.
The explosive run put Louisville ahead 35-31, giving the Cardinals a lead they would not surrender.
Brown's two touchdown runs accounted for 111 yards by themselves.
His performance also came on his birthday, giving Louisville's running back an especially memorable afternoon. Head coach Jeff Brohm praised Brown's physical running and credited the Cardinals' offensive line for helping the rushing attack break through against a ranked opponent.
SMU still had time to respond.
Instead, Louisville's defense produced another pivotal stop.
Louisville Turns Fourth-Down Stops Into Touchdowns
SMU accumulated plenty of offense throughout the afternoon, but several promising possessions ended without points.
The Mustangs were stopped twice on fourth down.
Both times, Louisville responded by driving for touchdowns.
Those sequences became increasingly important in a game decided by 10 points.
SMU actually finished with more total offense than Louisville. The Mustangs gained 479 yards compared with Louisville's 442, ran 20 more plays and possessed the ball for nearly four additional minutes.
But Louisville consistently turned its opportunities into points while forcing SMU into costly mistakes.
Isaac Brown Gives Louisville Breathing Room
After Keyjuan Brown's second long touchdown put Louisville ahead 35-31, the Cardinals needed one more score to create separation.
Isaac Brown supplied it.
The Louisville running back scored on a 27-yard touchdown with 5:32 remaining, extending the Cardinals' advantage to 41-31.
It proved to be the final score of the afternoon.
Louisville's two Browns had delivered three major second-half touchdown runs: Keyjuan from 58 and 53 yards and Isaac from 27.
SMU still had enough time to make the finish interesting.
Jennings drove the Mustangs toward the Louisville goal line looking to cut the deficit to three.
Then came the play that effectively ended the game.
Louisville Forces Goal-Line Fumble
Jennings scrambled toward the end zone from 19 yards out with less than three minutes remaining.
He appeared headed for a touchdown.
Louisville's defense knocked the football loose just before Jennings crossed the goal line. The ball rolled through the end zone and out of bounds, resulting in a touchback with 2:43 remaining.
Instead of pulling within one possession, SMU had committed its third turnover.
Louisville took possession and closed out its first victory over the Mustangs.
Turnovers Decide a Game SMU Led Statistically
The final statistics illustrated why the outcome was especially frustrating for SMU.
The Mustangs had more yards, more plays and more possession time.
They also had Raphael's 197 rushing yards.
But Louisville won the turnover battle 3-0.
Jennings completed 24 of 35 passes for 222 yards and a touchdown, but he threw two interceptions.
Both were made by Louisville defensive back Kaleb Beasley.
The late fumble gave Louisville its third takeaway.
For the Cardinals, the clean performance with the football continued an impressive early-season trend. Louisville has gone three consecutive games without committing a turnover.
Lincoln Kienholz Helps Louisville Produce 442 Yards
Louisville did not need a huge passing performance because of the production from its running backs.
Kienholz completed 14 of 23 passes for 177 yards and two touchdowns. He also added a rushing score as Louisville accumulated 442 yards of total offense.
The Cardinals' ability to create explosive plays on the ground became the defining offensive difference.
Louisville entered the afternoon searching for more big-play production from its rushing attack.
It found it against a ranked ACC opponent.
Louisville Overcomes 11 Penalties
The Cardinals' performance was far from mistake-free.
Louisville committed 11 penalties for 110 yards, its highest penalty yardage since being assessed 121 yards against Miami in 2019.
Seven of those penalties were classified as personal fouls, unsportsmanlike conduct or unnecessary roughness.
The Cardinals managed to overcome those mistakes because they avoided turnovers and produced explosive plays.
Louisville also dealt with difficult conditions.
The kickoff temperature was 95 degrees, making it the second-hottest home game in Cardinals history. Only the 98-degree kickoff against Murray State in 2011 was hotter.
Louisville Records First Victory Over SMU
Saturday's result also carried historical significance.
Louisville had never defeated SMU before this matchup.
The Cardinals earned that first victory with a second-half rushing performance that repeatedly punished the Mustangs.
It also gave Louisville its fifth victory over a ranked opponent in four seasons under Brohm.
For SMU, the loss was unusual for another reason.
Before Saturday, the Mustangs were 16-1 under Rhett Lashlee when gaining at least 475 yards and outgaining their opponent. Their only previous loss under those circumstances came against California in November 2025.
Against Louisville, the Mustangs again won the yardage battle but not the game.
Louisville and SMU Turn to Next Week
SMU will return home to face Missouri State, while Louisville remains home to play Wake Forest.
Both teams leave Saturday with plenty to evaluate.
SMU proved it could move the football against a ranked opponent, with Raphael producing 197 yards and three scores. But two failed fourth downs and three turnovers erased much of that production.
Louisville found the explosive running game it had been missing.
Keyjuan Brown needed only 10 carries to produce a career-high 163 yards, and his two long touchdowns helped Louisville answer whenever SMU appeared ready to take control.
When the Cardinals needed one final defensive play, they got that too, forcing Jennings' goal-line fumble to close the door.
Behind Keyjuan Brown's career day and a 3-0 advantage in turnovers, No. 23 Louisville defeated No. 16 SMU 41-31 for its first victory over the Mustangs in program history.









